WebATF6α is constitutively expressed as pATF6α(P) (~90-kDa protein), and converted to pATF6α(N) (>50-kDa protein) in ER-stressed cells. Fig.2 Western blot analysis of mouse … WebThe fully glycosylated form of ATF6, a 670 amino acid protein, exhibits an electrophoretic mobility of ~90 kDa in denaturing SDS-gels, in part because of the glycosylated …
ATF-6 (D4Z8V) Rabbit mAb Cell Signaling Technology
WebFigure 3: ATF6 regulates KC activation and liver IRI. (A) ATF6 KD diminishes ischemia-induced pro-inflammatory priming of liver innate immune cells. KCs, isolated from groups … WebApr 8, 2024 · Figure 3. (A) In its inactivated state, ATF6 is a 90 kD ER transmembrane protein that is anchored in the membrane by GRP78.(B) Upon ER stress, GRP78 … how to optimize imports in intellij
Unfolded protein response is activated by BBR. (A) Expression of …
Web描述. Rabbit Monoclonal Antibody to ERK1. 研究背景. Mitogen-activated protein kinase (MAPK) signaling pathways involve two closely related MAP kinases, known as extracellular-signal-related kinase 1 (ERK 1, p44) and 2 (ERK 2, p42). Growth factors, steroid hormones, G protein-coupled receptor ligands and neurotransmitters can initiate … WebAug 1, 2024 · ATF6 regulates ER protein folding capacity by promoting the expression of ER chaperones such as the 78-kDa glucose-regulated protein (GRP78). ER-resident chaperones like GRP78 prevent and/or resolve ER polypeptide accumulation and subsequent ER stress-induced UPR activation by folding nascent polypeptides. Web43 kDa 26 kDa 500 m Avh262 GFP WB: anti-GFP # GFP Avh262 GFP Avh262 d ** GFP Avh262 Avh262 GFP # 43 kDa 26 kDa WB: anti-GFP GFP Avh262 Diameter of the ... J., Chen, X., Hendershot, L. & Prywes, R. ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals. Dev. Cell … mvp twitter